LINZESS is available in a once-daily dose for the following indications1

For adults with IBS-C | 290 mcg

For adults with CIC |
2 dosing options

For functional constipation (FC) in pediatric patients 6 to 17 years of age | 72 mcg

LINZESS dosing tablet containers
LINZESS dosing tablet containers
LINZESS dosing tablet containers
LINZESS dosing tablet containers

For adults with IBS-C | 290 mcg

LINZESS dosing tablet containers

For adults with CIC | 2 dosing options

LINZESS dosing tablet containersLINZESS dosing tablet containers

For functional constipation (FC) in pediatric patients 6 to 17 years of age | 72 mcg

LINZESS dosing tablet containers

For IBS-C | 290 mcg

LINZESS dosing tablet containers

For CIC | 2 dosing options

LINZESS dosing tablet containers
LINZESS dosing tablet containers

ICD-10 diagnosis codes2

For IBS-C*

290 mcg

K58.1

For CIC*

145 mcg | 72 mcg

K59.04

For FC

72 mcg

K59.04

For informational purposes only. It is the responsibility of the healthcare provider to determine the appropriate code(s) for services provided to his or her patient. Nothing in this website is intended to serve as reimbursement advice, a guarantee of coverage, or a guarantee of payment for LINZESS.

*For adult patients.

For pediatric patients 6 to 17 years of age.

CIC, chronic idiopathic constipation; FC, functional constipation; IBS-C, irritable bowel syndrome with constipation.

LINZESS should be taken1:

LINZESS capsule icon

Every day

LINZESS once-a-day icon

Once a day

LINZESS empty stomach icon

On an empty stomach and at least 30 minutes prior to a meal

LINZESS clock icon

At approximately the same time each day

For patients who are unable to swallow the capsule whole,
LINZESS capsules can be opened and administered orally either in applesauce or with water.

Clinical considerations1

  • Duration of use is not limited
  • No drug-drug interactions are anticipated
  • Negligible systemic availability